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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2234192Generated: October 30, 2026

Hydrogen Bromide → AZD-3199 dihydrobromide

https://huagongshe.com/reaction/2234192

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrogen BromideHCID 260—
ReactantAzd-3199HCID 16035068—
SolventEthanolHCID 702—
ProductAZD-3199 dihydrobromideHCID 25031637—

Reaction Steps

N-[2-(Diethylamino)ethyl]-N-(2-{[2-(4-hydroxy-2-oxo-2,3-dihydro-1,3-benzothiazol-7-yl)ethyl]amino}ethyl)-3-[2-(1-naphthyl)ethoxy]propanamide prepared as described in Example 7 (52 mg) was dissolved in ethanol (1.5 ml) and treated with 48% hydrobromic acid (21 μl). The white solid dihydrobromide salt was collected by filtration. Yield 58 mg.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07709511B2
Source datasetuspto-grants-2010_05
ORD IDord-a0a8a0c0fe8742d388cf43fd83a924dc
Source noteuspto-grants-2010_05