huagongshe.com
HRID2234233

反应详情

EQUATION

反应方程式

HRID 2234233 的结构方程式

REACTANTS

反应物

1
结构：CN(C)CCC(Oc1cccc2ccccc12)c1cccs1.O=C([O-])[C@@H](O)[C@H](O)C(=O)[O-]
HCID86625060

未命名化合物

PRODUCTS

生成物

1
结构：CN(C)CC[C@H](Oc1cccc2ccccc12)c1cccs1.O=C([O-])[C@@H](O)[C@H](O)C(=O)[O-]
HCID86625059

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

(RS)-N,N-dimethyl-3-(naphthyloxy)-3-(2-thienyl)propylamine-D-tartrate (461 g) is dissolved in ethanol (700 ml) under reflux. After gradual cooling to lab temperature, the mixture is stirred for 164 hours. The precipitated crystals are sucked off and washed with ethanol. The yield is 150 g (32%). Optical purity is 98% ee (CE).

WORKUP

后处理

  1. temperatureunder reflux
  2. temperatureAfter gradual cooling to lab temperature
  3. washwashed with ethanol