Hydroxyacetone → HCID 46928098, compound

HRID 2234235Notes

Reaction equation

HRID 2234235 reaction equation
[CH3:1][C:2]([CH2:4][OH:5])=[O:3].[C:6]([C:10]([C:13](F)=[O:14])([F:12])[F:11])([F:9])([F:8])[F:7]>C(N(CC)CC)C>[CH3:1][C:2]([CH2:4][O:5][C:13]([C:10]([C:6]([F:9])([F:8])[F:7])([F:12])[F:11])=[O:14])=[O:3]

Participants

4

Reactant 2

HCID 8299HydroxyacetoneHCID 67912Perfluoropropionyl fluoride

Product 1

HCID 46928098HCID 46928098, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

CH3COCH2OH (50.0 g) and triethylamine (225.4 g) were put into a flask and stirred under cooling in an ice bath. CF3CF2COF (377.5 g) diluted with nitrogen gas was blown into the flask over a period of 4 hours, while maintaining the internal temperature to be at most 10° C. Then, the mixture was stirred at room temperature for 2 hours and then added to 500 mL of ice water.

Workup

  1. temperatureunder cooling in an ice bath
  2. temperaturewhile maintaining the internal temperature
  3. customto be at most 10° C
  4. stirringThen, the mixture was stirred at room temperature for 2 hours

Sources & evidence

ORD record
ord-0c68c2c3f285424e92c2d8858166dcb6
Source dataset
uspto-grants-2010_05
Patent number
US07709665B2

Reaction notes

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