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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2234355Generated: October 30, 2026

HCID 43234129, compound → 1-Cyclopropylpiperidin-4-amine

https://huagongshe.com/reaction/2234355

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 43234129HCID 43234129—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product1-Cyclopropylpiperidin-4-amineHCID 16227644—

Reaction Conditions

Temperature30 °C

Reaction Steps

N-benzyl-1-cyclopropyl-piperidin-4-amine (Intermediate 25; 2.3 g 10 mmol), 10% Palladium on Carbon (230 mg) and Methanol (230 mL) were combined and heated with stirring at 30° C. under Hydrogen at 5 bar pressure for 16 hours.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07709471B2
Source datasetuspto-grants-2010_05
ORD IDord-a08177c815a7467f98aa55f3f6bbf70f
Source noteuspto-grants-2010_05