3-Methyl-4-nitrobenzoic acid → HCID 43373277, compound

HRID 2234379Notes

Reaction equation

HRID 2234379 reaction equation
F[C:2]1[CH:17]=[C:16]([N+:18]([O-])=O)[CH:15]=[CH:14][C:3]=1[C:4]([NH:6][CH:7]1[CH2:12][CH2:11][N:10]([CH3:13])[CH2:9][CH2:8]1)=[O:5].[CH3:21]C1C=C(C=CC=1[N+]([O-])=O)C(O)=O>>[NH2:18][C:16]1[CH:15]=[CH:14][C:3]([C:4]([NH:6][CH:7]2[CH2:12][CH2:11][N:10]([CH3:13])[CH2:9][CH2:8]2)=[O:5])=[CH:2][C:17]=1[CH3:21]

Participants

3

Reactant 2

HCID 183703-Methyl-4-nitrobenzoic acidHCID 580097692-Fluoro-N-(1-methyl-4-piperidinyl)-4-nitrobenzamide

Product 1

HCID 43373277HCID 43373277, compound

Procedure

The following intermediate was prepared in a manner analogous to Intermediate 62 utilising 3-Methyl-4-nitrobenzoic acid, available form Aldrich, as the starting Nitro acid.

Sources & evidence

ORD record
ord-3d7417773e4a4f08b78cb30925ee5eed
Source dataset
uspto-grants-2010_05
Patent number
US07709471B2

Reaction notes

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