3-Methyl-4-nitrobenzoic acid → HCID 31098231, compound

HRID 2234380Notes

Reaction equation

HRID 2234380 reaction equation
F[C:2]1[CH:17]=[C:16]([N+:18]([O-:20])=[O:19])[CH:15]=[CH:14][C:3]=1[C:4]([NH:6][CH:7]1[CH2:12][CH2:11][N:10]([CH3:13])[CH2:9][CH2:8]1)=[O:5].[CH3:21]C1C=C(C=CC=1[N+]([O-])=O)C(O)=O>>[CH3:21][C:17]1[CH:2]=[C:3]([CH:14]=[CH:15][C:16]=1[N+:18]([O-:20])=[O:19])[C:4]([NH:6][CH:7]1[CH2:12][CH2:11][N:10]([CH3:13])[CH2:9][CH2:8]1)=[O:5]

Participants

3

Reactant 2

HCID 183703-Methyl-4-nitrobenzoic acidHCID 580097692-Fluoro-N-(1-methyl-4-piperidinyl)-4-nitrobenzamide

Product 1

HCID 31098231HCID 31098231, compound

Procedure

3-methyl-N-(1-methyl-4-piperidyl)-4-nitro-benzamide was prepared in a manner analogous to Intermediate 62 utilising 3-Methyl-4-nitrobenzoic acid, available form Aldrich, as the starting Nitro acid.

Sources & evidence

ORD record
ord-7f88a8c26b7c4c7aaa668e1cdb54dc74
Source dataset
uspto-grants-2010_05
Patent number
US07709471B2

Reaction notes

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