Potassium Carbonate → HCID 58154169, compound

HRID 2234420Notes

Reaction equation

HRID 2234420 reaction equation
[CH2:1]([O:3][C:4]([C:6]1([CH2:9][NH:10][CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)[CH2:8][CH2:7]1)=[O:5])[CH3:2].C(=O)([O-])[O-].[K+].[K+].[Cl:22][C:23]1[N:28]=[C:27](Cl)[C:26]([N+:30]([O-:32])=[O:31])=[CH:25][N:24]=1>CC(C)=O>[CH2:1]([O:3][C:4]([C:6]1([CH2:9][N:10]([C:25]2[C:26]([N+:30]([O-:32])=[O:31])=[CH:27][N:28]=[C:23]([Cl:22])[N:24]=2)[CH:11]2[CH2:12][CH2:13][CH2:14][CH2:15]2)[CH2:7][CH2:8]1)=[O:5])[CH3:2]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 5212662,4-Dichloro-5-nitropyrimidineHCID 58153972Ethyl1-[(cyclopentylamino)methyl]cyclopropane-1-carboxylate

Product 1

HCID 58154169HCID 58154169, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a stirred solution of Ethyl1-[(cyclopentylamino)methyl]cyclopropane-1-carboxylate in acetone (700 mL) at room temperature was added potassium carbonate (29.0 g, 209.6 mmol) followed by the 2,4-dichloro-5-nitropyrimidine (Frontier Scientific; 29.81 g, 153.7 mmol).

Sources & evidence

ORD record
ord-e7ee3cdee14d4239a70a65d48116bbbc
Source dataset
uspto-grants-2010_05
Patent number
US07709471B2

Reaction notes

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