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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2234461Generated: October 26, 2026

1-Ethylpiperidin-4-amine → N-(1-ethyl-4-piperidyl)-3-methoxy-4-nitro-benzamide

https://huagongshe.com/reaction/2234461

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Ethylpiperidin-4-amineHCID 3734990—
Reactant3-methoxy-N-[(3R)-1-methylpyrrolidin-3-yl]-4-nitro-benzamideHCID 68683036—
ProductN-(1-ethyl-4-piperidyl)-3-methoxy-4-nitro-benzamideHCID 68681536—

Reaction Steps

The title compound was prepared by an analogous method to the preparation of Intermediate 188, on a 9.28 mmol scale utilising 1-ethylpiperidin-4-amine (Fluorochem; 1.19 g, 9.28 mmol), as a brown solid (3.3 g, 100%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07709471B2
Source datasetuspto-grants-2010_05
ORD IDord-efde4b69e3844a7a8d46a2507a312c48
Source noteuspto-grants-2010_05