HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Dimethyl-1,3-propanediamine → 4-amino-3-chloro-N-(3-dimethylaminopropyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Dimethyl-1,3-propanediamine | HCID 7993 | — |
| Reactant | 4-amino-3-chloro-N-(1-ethyl-4-piperidyl)benzamide | HCID 64321494 | — |
| Product | 4-amino-3-chloro-N-(3-dimethylaminopropyl)benzamide | HCID 64318137 | — |
Reaction Steps
The title compound was prepared by an analogous method to the preparation of Intermediate 212, on a 15 mmol scale utilising 3-Dimethylamino-1-propylamine (Aldrich; 1.685 g, 16.5 mmol), as a tan coloured solid (3.25 g, 85%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07709471B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-0322277ba13746f9a1ec58a9ac7b2898 |
| Source note | uspto-grants-2010_05 |