HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 15225176, compound → (2R)-Acetamido(cyclohexyl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 15225176 | HCID 15225176 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (2R)-Acetamido(cyclohexyl)acetic acid | HCID 10921523 | 75% |
Reaction Steps
To a solution of 15 g of (R)-(acetylamino) (1,4-cyclohexadiene-1-yl)acetic acid in 500 mL of methanol was added 500 mg of platinum oxide, and the mixture was stirred for 4 hours under hydrogen gas atmosphere. Then, the reaction mixture was filtrated and the filtrate was condensed. The residue was recrystallized from ethanol to give 11.4 g (75%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07713972B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-05d03532a94b489f8d4e2f61c55f6449 |
| Source note | uspto-grants-2010_05 |