反应详情

2.4 g (11.6 mmol) of triazine 2a and 7 ml (106 mmol) of acrylonitrile are placed in 24 ml of a solution of pyridine and water (1:1) at reflux for 3 h. After concentration the reaction medium is extracted by AcOEt, and after drying on MgSO4 the organic phases are dry concentrated. 2.8 g of solid 3a are isolated and then washed with ether (yield=93%). TLC silica gel 60 F 254 Merck, petroleum ether:AcOEt 70:30, Rf=0.18.

1. temperatureat reflux for 3 h
2. concentrationAfter concentration the reaction medium
3. extractionis extracted by AcOEt
4. customafter drying on MgSO4 the organic phases
5. customare dry
6. concentrationconcentrated