HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-3-fluorobenzenesulfonyl chloride → 4-Bromo-N-{4-[cis-3,5-dimethyl-1-piperazinyl]-2-pyridinyl}-3-fluorobenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-3-fluorobenzenesulfonyl chloride | HCID 2778218 | — |
| Reactant | 4-[cis-3,5-Dimethyl-1-piperazinyl]-2-pyridinamine | HCID 58988129 | — |
| Reactant | 4-Bromo-N-(2-chloro-4-pyridinyl)benzenesulfonamide | HCID 58988139 | — |
| Product | 4-Bromo-N-{4-[cis-3,5-dimethyl-1-piperazinyl]-2-pyridinyl}-3-fluorobenzenesulfonamide | HCID 58988153 | — |
Reaction Steps
The title compound was prepared in a manner similar to 4-bromo-N-(2-chloro-4-pyridinyl)benzenesulfonamide (D3) using 4-[cis-3,5-dimethyl-1-piperazinyl]-2-pyridinamine (D21) and 4-bromo-3-fluorobenzenesulfonyl chloride as the starting materials. MS (ES+) m/e 443, 445 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07713978B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-dcd55ef8d9d444acb3317c19a62510e4 |
| Source note | uspto-grants-2010_05 |