HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-[5-[cis-3,5-dimethyl-4-(phenylmethyl)-1-piperazinyl]-2-(methyloxy)-3-pyridinyl]-2,2,2-trifluoroacetamide → N-{5-[cis-3,5-Dimethyl-1-piperazinyl]-3-pyridinyl}-2,2,2-trifluoroacetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-[5-[cis-3,5-dimethyl-4-(phenylmethyl)-1-piperazinyl]-2-(methyloxy)-3-pyridinyl]-2,2,2-trifluoroacetamide | HCID 58988127 | — |
| Reactant | 1,1-Dimethylethyl {5-[cis-3,5-dimethyl-1-piperazinyl]-3-pyridinyl}carbamate | HCID 58988138 | — |
| Product | N-{5-[cis-3,5-Dimethyl-1-piperazinyl]-3-pyridinyl}-2,2,2-trifluoroacetamide | HCID 58988131 | — |
Reaction Steps
The title compound was prepared in a manner similar to N-[5-[cis-3,5-dimethyl-4-(phenylmethyl)-1-piperazinyl]-2-(methyloxy)-3-pyridinyl]-2,2,2-trifluoroacetamide (D28) using 1,1-dimethylethyl {5-[cis-3,5-dimethyl-1-piperazinyl]-3-pyridinyl}carbamate (D34) as the starting material. MS (ES+) m/e 303 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07713978B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-bc76183db86b4a8684efb657874f148b |
| Source note | uspto-grants-2010_05 |