1,4-Dioxane hydrochloride → HCID 68682431, compound

Participants

Reaction Steps

1,1-Dimethylethyl (2R,6S)-4-[6-({[2-chloro-4-(4-methyl-2-thienyl)phenyl]sulfonyl}amino)-5-(methyloxy)-2-pyridinyl]-2,6-dimethyl-1-piperazinecarboxylate (D14) (0.128 g) was dissolved in dioxane (5 mL) and 4N HCl/dioxane (5 mL) added and the reaction stirred at rt for 24 hours. The reaction mixture was evaporated to give the title compound as a pale yellow solid (E6) (0.111 g). MS (ES+) m/e 507/509 [M+H]+.

Provenance & Evidence