HCID 70882504, compound → HCID 68682630, compound

Participants

Reaction Conditions

Reaction Steps

1,1-Dimethylethyl (2R,6S)-4-[6-({[2-chloro-4-(3-furanyl)phenyl]sulfonyl}amino)-5-(methyloxy)-2-pyridinyl]-2,6-dimethyl-1-piperazinecarboxylate (D15) (0.170 g) was dissolved in 4N HCl/dioxane (6 mL) and the reaction stirred at 35° C. for 2 hours. The reaction mixture was evaporated and triturated with ethyl acetate/ether (×3) to give a white solid which was dried at 50° C. under high vac to give the compound as a white solid (E7)(0.119 g). MS (ES+) m/e 477/479 [M+H]+.

Provenance & Evidence