Water → HCID 136110688, compound

Participants

Reaction Steps

1 g of 1-benzyl-4-chloro-2-(4-n-butoxyphenyl)imidazole-5-acetic acid was boiled in 14 ml of 48% hydrobromic acid for 2 hours, and addition of 15 ml of water, followed by allowing the solution to stand, resulted in crystals deposited. Recrystallization of the crystals from aqueous ethanol yielded 0.5 g of 1-benzyl-4-chloro-2-(4-hydroxyphenyl)imidazole-5-acetic acid as colorless, prism-formed crystals, m.p. 140°-145° C.

Provenance & Evidence