Cycloheptylamine → HCID 11688683, compound

Participants

Reaction Conditions

Reaction Steps

Charge vial with 3-(2,4-dichloro-benzyl)-dihydro-furan-2-one (300 mg, 1.2 mmol) and cycloheptylamine (139 mg, 1.2 mmol) and heat to 140° C. for 3 hours. Then heat to 195° C. overnight. Cool to room temperature and purify over silica gel which affords 135 mg (32%) of the title compound: Mass spectrum (apci) m/z=340.2 (M+H).

Provenance & Evidence