HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 59299489, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 3-Chloro-2-methylbenzenesulfonyl chloride | HCID 522734 | — |
| Reactant | HCID 59299405 | HCID 59299405 | — |
| Product | HCID 59299489 | HCID 59299489 | 47.2% |
Reaction Steps
Using the procedure to synthesize Example 207 and using reagents 3-Chloro-2-methyl-benzenesulfonyl chloride (194 mg, 0.84 mmol), pyridine (0.07 mL, 0.84 mmol), and 3-(3-Amino-2,6-dichloro-benzyl)-1-cyclohexyl-pyrrolidin-2-one (Example 192) (240 mg, 0.70 mmol) affords 175 mg (47%) of the title compound: Mass spectrum (apci) m/z=529.05 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07713979B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-8ca401d3209a41a4bac1cb20eed1f1bf |
| Source note | uspto-grants-2010_05 |