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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2235319Generated: October 31, 2026

Hydrochloric Acid → HCID 178479619, compound

https://huagongshe.com/reaction/2235319

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 178455340HCID 178455340—
SolventMethanolHCID 887—
ProductHCID 178479619HCID 178479619147.4%

Reaction Conditions

Temperature40 °C

Reaction Steps

Add HCl (0.015 mL) to 1-[cis-4-(tert-butyl-dimethyl-silanyloxy)-cyclohexyl]-3-(2,6-dichloro-4-pyridin-3-yl-benzyl)-pyrrolidin-2-one (Preparation 75) (0.027 G, 0.0506 mmol) in methanol (2 mL) and heat to 40° C. for 1 hour. Concentrate under reduced pressure to give the title compound (0.017 g): mass spectrum (m/z):420(M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07713979B2
Source datasetuspto-grants-2010_05
ORD IDord-7aa50012cc1b4622afb0ab9d78b7c9f9
Source noteuspto-grants-2010_05