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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2235409Generated: October 29, 2026

5-Amino-3,3-dimethyl-6-nitro-1-pentyl-1,3-dihydro-indol-2-one → 3-(3-Amino-phenyl)-N-(3,3-dimethyl-6-nitro-2-oxo-1-pentyl-2,3-dihydro-1H-indol-5-yl)-propionamide

https://huagongshe.com/reaction/2235409

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Amino-3,3-dimethyl-6-nitro-1-pentyl-1,3-dihydro-indol-2-oneHCID 17802744—
Reactant3-(3-Amino-phenyl)-propionyl chlorideHCID 23092661—
Product3-(3-Amino-phenyl)-N-(3,3-dimethyl-6-nitro-2-oxo-1-pentyl-2,3-dihydro-1H-indol-5-yl)-propionamideHCID 23092670—

Reaction Steps

The compound is synthesized from A8 (213 mg) and freshly prepared 3-(3-amino-phenyl)-propionyl chloride (223 mg; 1.21 mmol) as described in Example 1a.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07714010B2
Source datasetuspto-grants-2010_05
ORD IDord-c104b7bfab444d4bb93d6b99ccf5cb60
Source noteuspto-grants-2010_05