反应详情

2-Formyl-5-hydroxymethylpyridine (0.1 mole) in 100 ml. of tetrahydrofuran is treated with 0.11 mole of thionyl chloride, and the mixture is refluxed 3 hours. The product, 2-formyl-5-chloromethylpyridine hydrochloride is collected by filtration from the cooled reaction mixture.

1. temperaturethe mixture is refluxed 3 hours
2. filtrationThe product, 2-formyl-5-chloromethylpyridine hydrochloride is collected by filtration from the cooled reaction mixture