Ammonium Hydroxide → Jpc 80

HRID 223543Notes

Reaction equation

HRID 223543 reaction equation
Cl.[CH3:2][C:3]1[C:8]([OH:9])=[C:7]([CH2:10][SH:11])[C:6]([CH:12]=[CH2:13])=[CH:5][N:4]=1.[OH-:14].[NH4+:15]>O>[CH3:2][C:3]1[C:8]([OH:9])=[C:7]([CH2:10][S:11][S:11][CH2:10][C:7]2[C:6]([CH:12]=[CH2:13])=[CH:5][N:15]=[C:3]([CH3:2])[C:8]=2[OH:14])[C:6]([CH:12]=[CH2:13])=[CH:5][N:4]=1

Participants

4

Reactant 2

HCID 14923Ammonium HydroxideHCID 20263928HCID 20263928, compound

Product 1

HCID 171428Jpc 80

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

2-Methyl-3-hydroxy-4-mercaptomethyl-5-vinylpyridine hydrochloride (9 g.) is dissolved in 50 ml. water and treated with 2 N ammonium hydroxide to about pH 9. Air is bubbled through the solution for 24 hours. The precipitated bis[2-methyl-3-hydroxy-5-vinyl-4-pyridylmethyl]disulfide is collected on a filter and dried, m.p. 178°-180° (dec.).

Workup

  1. customAir is bubbled through the solution for 24 hours
  2. customThe precipitated bis[2-methyl-3-hydroxy-5-vinyl-4-pyridylmethyl]disulfide is collected on
  3. filtrationa filter
  4. customdried

Sources & evidence

ORD record
ord-d2b36343367b4529bf32a01f214e48c6
Source dataset
uspto-grants-1982_10
Patent number
US04355034

Reaction notes

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