Hydrochloric Acid → 3-(1-Methyl-1h-imidazol-2-yl)propanoic acid

HRID 2235432Notes

Reaction equation

HRID 2235432 reaction equation
C[O:2][C:3](=[O:12])[CH2:4][CH2:5][C:6]1[N:7]([CH3:11])[CH:8]=[CH:9][N:10]=1.Cl>>[CH3:11][N:7]1[CH:8]=[CH:9][N:10]=[C:6]1[CH2:5][CH2:4][C:3]([OH:12])=[O:2]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 674269261H-Imidazole-2-propanoic acid, 1-methyl-, methyl ester

Product 1

HCID 177503733-(1-Methyl-1h-imidazol-2-yl)propanoic acid

Procedure

3-(1-Methyl-1H-imidazol-2-yl)-propionic acid methyl ester (0.87 g) is treated with hydrochloric acid (6 N; 5 ml) at RT for 20 h. After evaporation of the solvent the compound (0.86 g) is obtained as hydrochloric salt.

Workup

  1. customAfter evaporation of the solvent the compound (0.86 g)
  2. customis obtained as hydrochloric salt

Sources & evidence

ORD record
ord-a921bc2abf8c455ea342771cfc222aff
Source dataset
uspto-grants-2010_05
Patent number
US07714010B2

Reaction notes

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