Nitric Acid → HCID 67426568, compound

Participants

Reaction Steps

To a solution of 1′-methyl-spiro[cyclopropane-1,3′-indoline]-2′-one (8 g) in acetic acid (150 ml) is added nitric acid (fuming, 5.5 ml) over a period of 15 min at 15° C. The mixture is stirred at RT for 3 h and then poured into water. The precipitate is collected by filtration and washed with water, 2-propanol and tertbutyl-methyl-ether to give the title compound (8.80 g).

Provenance & Evidence