HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67425846, compound → HCID 67427197, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67425846 | HCID 67425846 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 67427197 | HCID 67427197 | — |
Reaction Steps
Analogously to general procedure (II) the compound is prepared from 5′-amino-1′-methyl-6′-nitro-spiro[cyclopropane-1,3′-indoline]-2′-one (50 mg) in MeOH (10 ml) and hydrochloric acid (1 ml) using Pd/C (15.0 mg) as catalyst (3 h; 1 bar). After an aqueous work-up the compound is used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07714010B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-a717549f3e4c4e06a0c8b3a84bc6b685 |
| Source note | uspto-grants-2010_05 |