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HRID2235470

反应详情

EQUATION

反应方程式

HRID 2235470 的结构方程式

REACTANTS

反应物

2
结构：O=C=Nc1ccccc1
HCID7672

Phenyl isocyanate

C7H5NO

结构：CCCCCN1C(=O)C(C)(C)c2cc3[nH]c(N)nc3cc21
HCID59300824

未命名化合物

PRODUCTS

生成物

1
结构：CCCCCN1C(=O)C(C)(C)c2cc3[nH]c(NC(=O)Nc4ccccc4)nc3cc21
HCID59300829

未命名化合物

收率 63.3%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)=O
溶剂HCID180

Acetone

C3H6O

PROCEDURE

实验过程

A solution of D5 (172 mg) and phenyl isocyanate (72 mg; 0.6 mmol) in acetone (3 ml) is stirred at RT for 3 days. Acetone is evaporated and the residue is purified by flash chromatography on silica gel eluted with CH2Cl2/MeOH (20:1) to give the desired compound (154 mg).

WORKUP

后处理

  1. customAcetone is evaporated
  2. customthe residue is purified by flash chromatography on silica gel
  3. washeluted with CH2Cl2/MeOH (20:1)