Thionyl Chloride → HCID 67426354, compound

HRID 2235478Notes

Reaction equation

HRID 2235478 reaction equation
O[CH2:2][C:3]1[NH:22][C:6]2=[CH:7][C:8]3[C:9]([CH3:21])([CH3:20])[C:10](=[O:19])[N:11]([CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[C:12]=3[CH:13]=[C:5]2[N:4]=1.S(Cl)([Cl:25])=O>C(Cl)(Cl)Cl>[Cl:25][CH2:2][C:3]1[NH:22][C:6]2=[CH:7][C:8]3[C:9]([CH3:21])([CH3:20])[C:10](=[O:19])[N:11]([CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[C:12]=3[CH:13]=[C:5]2[N:4]=1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 59300970HCID 59300970, compound

Product 1

HCID 67426354HCID 67426354, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Conditions

Temperature
60 °C

Procedure

E1 (330 mg) is dissolved in CHCl3 (5 ml), thionyl chloride (1.2 ml) is added and the mixture is stirred at 60° C. for 15 h. The reaction mixture is concentrated in vacuo to give the compound.

Workup

  1. concentrationThe reaction mixture is concentrated in vacuo
  2. customto give the compound

Sources & evidence

ORD record
ord-c882e97962164686bf276b409c0e46c9
Source dataset
uspto-grants-2010_05
Patent number
US07714010B2

Reaction notes

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