Benzyl Chloride → HCID 20264049, compound

HRID 223551Notes

Reaction equation

HRID 223551 reaction equation
[OH:1][C:2]1[C:3]([CH3:12])=[N:4][CH:5]=[C:6]([CH:10]=[CH2:11])[C:7]=1[CH2:8][OH:9].C(=O)([O-])[O-].[K+].[K+].[CH2:19](Cl)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>CC(C)=O>[CH3:12][C:3]1[C:2]([O:1][CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[C:7]([CH2:8][OH:9])[C:6]([CH:10]=[CH2:11])=[CH:5][N:4]=1

Participants

5

Reactant 3

HCID 7503Benzyl ChlorideHCID 11430Potassium CarbonateHCID 13066945HCID 13066945, compound

Product 1

HCID 20264049HCID 20264049, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a mixture of 0.1 mole 3-hydroxy-4-hydroxymethyl-2-methyl-5-vinylpyridine in 500 ml. of acetone and 25 gm. potassium carbonate is added 0.11 mole of benzyl chloride. The reaction mixture is stirred overnight, filtered, and the acetone removed in vacuo to yield 2-methyl-3-benzyloxy-4-hydroxymethyl-5-vinylpyridine.

Workup

  1. filtrationfiltered
  2. customthe acetone removed in vacuo

Sources & evidence

ORD record
ord-f87a756b26d74b1095ed50657342e113
Source dataset
uspto-grants-1982_10
Patent number
US04355034

Reaction notes

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