反应详情

To a solution containing 0.06 g (0.18 mmol) of 1-(2-hydroxy-3-nitrophenyl)-3-mesitylthiourea in acetonitrile was added 0.10 g (0.36 mmol) of mercury (II) chloride, and the mixture was then stirred for 1 h. The reaction mixture was diluted with ethyl acetate (2 ml) and filtered through a prepacked celite column. The filtrate was concentrated under reduced pressure and the residue was purified via Biotage chromatography eluting with 20% ethyl acetate/dichloromethane to afford 0.047 g (90%) of product.

1. filtrationfiltered through a prepacked celite column
2. concentrationThe filtrate was concentrated under reduced pressure
3. customthe residue was purified via Biotage chromatography
4. washeluting with 20% ethyl acetate/dichloromethane