反应详情

To a nitrogen inerted slurry of 2.24 g (11.5 mmol) of 3-methyl-4-nitro-1,3-dihydroimidazo[4,5-c]pyridin-2-one in 25 mL of methanol was added 0.5 mL of Raney nickel (50% slurry in water). The reaction slurry was purged with hydrogen and then stirred under balloon pressure hydrogen for 1 h. To the reaction slurry was added 20 mL of methanol and the reaction slurry was purged with hydrogen and then stirred under balloon pressure hydrogen for 2 h.

1. customThe reaction slurry was purged with hydrogen
2. additionTo the reaction slurry was added 20 mL of methanol
3. customthe reaction slurry was purged with hydrogen
4. stirringstirred under balloon pressure hydrogen for 2 h.