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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2235744Generated: October 30, 2026

tert-butyl N'-[5-chloro-2-(4-fluorophenyl)-2-methoxypentanoyl]hydrazinecarboxylate → 5-Chloro-2-(4-fluorophenyl)-2-methoxyvaleric acid hydrazide monohydrochloride

https://huagongshe.com/reaction/2235744

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl N'-[5-chloro-2-(4-fluorophenyl)-2-methoxypentanoyl]hydrazinecarboxylateHCID 67067169—
SolventHydrochloric AcidHCID 313—
Solvent1,4-DioxaneHCID 31275—
Product5-Chloro-2-(4-fluorophenyl)-2-methoxyvaleric acid hydrazide monohydrochlorideHCID 67067176216.8%

Reaction Steps

tert-Butyl N′-[5-chloro-2-(4-fluorophenyl)-2-methoxypentanoyl]hydrazinecarboxylate (90 mg) was dissolved in a solution of 4 N hydrogen chloride in dioxane (1 mL), and the reaction solution was stirred at room temperature for 70 minutes. The reaction solution was concentrated under reduced pressure to obtain 81 mg of the title compound. The property value of the compound is as follows.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07713993B2
Source datasetuspto-grants-2010_05
ORD IDord-676b75cb52ea411e938b4d0dbb5974ae
Source noteuspto-grants-2010_05