HCID 59853915, compound → HCID 59853913, compound

HRID 2235996Notes

Reaction equation

HRID 2235996 reaction equation
[CH:1]1[C:11]2[CH:10]=[CH:9][C:8]3[CH:12]=[CH:13][CH:14]=[CH:15][C:7]=3[C:6](=[C:16]3[CH2:21][CH2:20][N:19]([C:22](=[O:30])[CH2:23][NH:24][C:25](=[O:29])[O:26][CH2:27][CH3:28])[CH2:18][CH2:17]3)[C:5]=2[CH:4]=[CH:3][CH:2]=1>C(O)C.[H][H].[C].[Pd]>[CH:1]1[C:11]2[CH2:10][CH2:9][C:8]3[CH:12]=[CH:13][CH:14]=[CH:15][C:7]=3[C:6](=[C:16]3[CH2:17][CH2:18][N:19]([C:22](=[O:30])[CH2:23][NH:24][C:25](=[O:29])[O:26][CH2:27][CH3:28])[CH2:20][CH2:21]3)[C:5]=2[CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 1

HCID 59853915HCID 59853915, compound

Product 1

HCID 59853913HCID 59853913, compound

Reagents, catalysts & solvents 3

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolventHCID 178418361HCID 178418361, compoundSolvent

Procedure

100 mg of palladium carbon (10% w/v) was added to 105 mg (0.261 mmol) of ethyl 2-[4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-piperidinyl]-2-oxoethylcarbamate in 3 ml of ethanol, and they were stirred at 3.6 MPa in hydrogen gas atmosphere overnight. After the filtration, the solvent was evaporated under reduced pressure to obtain the title compound.

Workup

  1. filtrationAfter the filtration
  2. customthe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-98bc663c998e47b2b99877d35f383e54
Source dataset
uspto-grants-2010_05
Patent number
US07713957B2

Reaction notes

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