HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 58782529, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 2-Chloro-4-fluorobenzene-1-sulfonyl chloride | HCID 522846 | — |
| Reactant | HCID 58782555 | HCID 58782555 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 58782529 | HCID 58782529 | — |
Reaction Steps
To a solution of 42b (0.016 g, 0.035 mmol) and DIPEA (0.02 mL, 0.105 mmol) in DCM (1 mL) at RT was added 2-chloro-4-fluorobenzenesulfonyl chloride (104, 0.016 g, 0.07 mmol) and the mixture shaken overnight at rt. The reaction mixture was concentrated in vacuo and purified by reverse phase HPLC to afford II-296: ms (ES+) m/z 639 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07714018B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-51caa2d3b84447e39ed2d7d04caa856c |
| Source note | uspto-grants-2010_05 |