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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2236075Generated: October 30, 2026

Benzoyl chloride → N-(6-tert.-Butyloxycarbonyl-3-cyano-4,5,6,7-tetrahydro-thieno[2,3-c]pyridin-2-yl)-benzamide

https://huagongshe.com/reaction/2236075

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl chlorideHCID 7412—
Reactanttert-butyl 2-amino-3-cyano-4,7-dihydrothieno[2,3-c]pyridine-6(5H)-carboxylateHCID 2763861—
ProductN-(6-tert.-Butyloxycarbonyl-3-cyano-4,5,6,7-tetrahydro-thieno[2,3-c]pyridin-2-yl)-benzamideHCID 11646668—

Reaction Steps

Prepared according to general procedure A starting from 2-amino-3-cyano-4,7-dihydro-thieno[2,3-c]pyridine-6(5H)-carboxylic acid 1,1-dimethylethyl ester (compound A2) and benzoyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07714134B2
Source datasetuspto-grants-2010_05
ORD IDord-95bbd5edc57b46cca197e50bf9f3dd43
Source noteuspto-grants-2010_05