HCID 43430863, compound → HCID 86616318, compound

HRID 2236084Notes

Reaction equation

HRID 2236084 reaction equation
[C:1]([C:3]1[C:11]2[CH2:10][CH2:9][NH:8][CH2:7][C:6]=2[S:5][C:4]=1[NH:12][C:13](=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)#[N:2]>N1C=CC=CC=1>[C:1]([C:3]1[C:11]2[CH2:10][CH2:9][NH:8][CH:7]([C:4]([CH2:3][CH3:1])=[S:5])[C:6]=2[S:5][C:4]=1[NH:12][C:13](=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)#[N:2]

Participants

3

Reactant 1

HCID 43430863HCID 43430863, compound2×

Product 1

HCID 86616318HCID 86616318, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

100 mg of N-(3-cyano4,5,6,7-tetrahydro-thieno[2,3-c]pyridin-2-yl)-benzamide (compound B2) and 57 mg of ethylchlorothioformiate are dissolved in 2 ml of pyridine. After stirring for 3 hours at room temperature, the solvent is removed and the remaining residue recristallized from ethanol to obtain the desired product.

Workup

  1. customthe solvent is removed

Sources & evidence

ORD record
ord-564597229a7941d9af9f0df9b0904983
Source dataset
uspto-grants-2010_05
Patent number
US07714134B2

Reaction notes

Loading…