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HRID2236201

反应详情

EQUATION

反应方程式

HRID 2236201 的结构方程式

REACTANTS

反应物

3
结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：CC(C)(C)OC(=O)CBr
HCID79177

Acetic acid, bromo-, 1,1-dimethylethyl ester

C6H11BrO2

结构：O=[N+]([O-])c1ccc(N2CC(O)C2)nc1
HCID52937264

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)COC1CN(c2ccc([N+](=O)[O-])cn2)C1
HCID52937265

未命名化合物

收率 75.4%

PROCEDURE

实验过程

1-(5-Nitro-pyridin-2-yl)-azetidin-3-ol (176 mg, 0.9 mmol) was treated with 60% NaH in oil (108 mg, 2.7 mmol) and tert-butyl bromoacetate (199.7 uL, 1.35 mmol) as above to yield 210 mg of a yellow solid. ES-MS calcd for C14H19N3O5 (m/e) 309.32, obsd 310.2 (M+H).