HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid → 1-phenyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid {6-[(2-methoxy-ethyl)-methyl-amino]-pyridin-3-yl}-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid | HCID 14968245 | — |
| Reactant | N2-(2-methoxyethyl)-N2-methylpyridine-2,5-diamine | HCID 52937159 | — |
| Product | 1-phenyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid {6-[(2-methoxy-ethyl)-methyl-amino]-pyridin-3-yl}-amide | HCID 59301363 | — |
Reaction Steps
With a procedure similar to example 16 above, 1-phenyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid {6-[(2-methoxy-ethyl)-methyl-amino]-pyridin-3-yl}-amide was prepared from 1-phenyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid and N2-(2-methoxy-ethyl)-N2-methyl-pyridine-2,5-diamine. LCMS calcd for C20H20F3N5O2 (m/e) 419, obsd 420 (M+H). The NMR spectrum obtained on the sample is compatible with its structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07714126B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-f6ae86c971624c30aa6302378f5fa453 |
| Source note | uspto-grants-2010_05 |