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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2236307Generated: October 31, 2026

N2-(2-methoxyethyl)-N2-methylpyridine-2,5-diamine → 2-(2-Methoxy-phenyl)-4-trifluoromethyl-oxazole-5-carboxylic acid {6-[(2-methoxy-ethyl)-methyl-amino]-pyridin-3-yl}-amide

https://huagongshe.com/reaction/2236307

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN2-(2-methoxyethyl)-N2-methylpyridine-2,5-diamineHCID 52937159—
Reactant2-(2-Methoxy-phenyl)-4-trifluoromethyl-oxazole-5-carboxylic acidHCID 59301290—
Product2-(2-Methoxy-phenyl)-4-trifluoromethyl-oxazole-5-carboxylic acid {6-[(2-methoxy-ethyl)-methyl-amino]-pyridin-3-yl}-amideHCID 59301330—

Reaction Steps

With a procedure similar to example 1 above, 2-(2-methoxy-phenyl)-4-trifluoromethyl-oxazole-5-carboxylic acid {6-[(2-methoxy-ethyl)-methyl-amino]-pyridin-3-yl}-amide was prepared from 2-(2-methoxy-phenyl)-4-trifluoromethyl-oxazole-5-carboxylic acid and N2-(2-methoxy-ethyl)-N2-methyl-pyridine-2,5-diamine. LCMS calcd for C21H21F3N4O4 (m/e) 450, obsd 451 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07714126B2
Source datasetuspto-grants-2010_05
ORD IDord-adfbd45d9f094c868d507ef5ec08f84e
Source noteuspto-grants-2010_05