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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2236313Generated: October 30, 2026

2-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acid → HCID 59301457, compound

https://huagongshe.com/reaction/2236313

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenyl-5-(trifluoromethyl)-oxazole-4-carboxylic acidHCID 2776438—
ReactantHCID 59301328HCID 59301328—
ProductHCID 59301457HCID 59301457—

Reaction Steps

With a procedure similar to example 66 above, 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid {5-[(2-methoxy-ethyl)-methyl-amino]-pyridin-2-yl}amide was prepared from (2-methoxyethyl)-methyl-(6-nitropyridin-3-yl)-amine and 2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid. The product was isolated as a yellow solid (200 mg, 37% yield). HRMS m/z calcd for C20H19F3N4O3 [M+H]+: 421.1482; Found: 421.1481.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07714126B2
Source datasetuspto-grants-2010_05
ORD IDord-029b4cf8f928488d98f35f87a3ede356
Source noteuspto-grants-2010_05