HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dimethylpropylamine, (S)- → N-((1S)-1,2-dimethylpropyl)-3-fluoro-5-methoxy-4-(2-propynyloxy)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dimethylpropylamine, (S)- | HCID 6999788 | — |
| Reactant | 3-Fluoro-5-methoxy-4-(2-propynyloxy)benzoyl chloride | HCID 57445698 | — |
| Product | N-((1S)-1,2-dimethylpropyl)-3-fluoro-5-methoxy-4-(2-propynyloxy)benzamide | HCID 59301812 | — |
Reaction Steps
According to the same method as that of Production Example 1, (1S)-1,2-dimethylpropylamine was used in place of 2,2-dimethylpropylamine, 3-fluoro-5-methoxy-4-(2-propynyloxy)benzoyl chloride was used in place of 4-(2-propynyloxy)-3-methoxybenzoyl chloride to obtain N-((1S)-1,2-dimethylpropyl)-3-fluoro-5-methoxy-4-(2-propynyloxy)benzamide (hereinafter, described as the compound 49 of the present invention) represented by the formula:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07714168B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-eac582a4895b4f0b8a99c20a494ee928 |
| Source note | uspto-grants-2010_05 |