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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2236356Generated: October 25, 2026

1,2-Dimethylpropylamine, (S)- → N-((1S)-1,2-dimethylpropyl)-3-fluoro-5-methoxy-4-(2-propynyloxy)benzamide

https://huagongshe.com/reaction/2236356

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-Dimethylpropylamine, (S)-HCID 6999788—
Reactant3-Fluoro-5-methoxy-4-(2-propynyloxy)benzoyl chlorideHCID 57445698—
ProductN-((1S)-1,2-dimethylpropyl)-3-fluoro-5-methoxy-4-(2-propynyloxy)benzamideHCID 59301812—

Reaction Steps

According to the same method as that of Production Example 1, (1S)-1,2-dimethylpropylamine was used in place of 2,2-dimethylpropylamine, 3-fluoro-5-methoxy-4-(2-propynyloxy)benzoyl chloride was used in place of 4-(2-propynyloxy)-3-methoxybenzoyl chloride to obtain N-((1S)-1,2-dimethylpropyl)-3-fluoro-5-methoxy-4-(2-propynyloxy)benzamide (hereinafter, described as the compound 49 of the present invention) represented by the formula:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07714168B2
Source datasetuspto-grants-2010_05
ORD IDord-eac582a4895b4f0b8a99c20a494ee928
Source noteuspto-grants-2010_05