Boron tribromide → HCID 59300378, compound

Participants

Reaction Conditions

Reaction Steps

4-Bromo-2-fluoro-5-methoxy-benzaldehyde (100 mg, 0.43 mmol) is dissolved in CH2Cl2 and cooled to −78° C. and then BBr3 (2 mL, 1 M solution in CH2Cl2, 2 mmol) is added. The resulting mixture is allowed to stir at room temperature until no starting material is left. The reaction is quenched and the product is isolated after chromatography (60 mg, 57%). MS (ESI): 216.9 (M−1)−1.

Provenance & Evidence