HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 2-(4-aminophenyl)pyrrolidine-1-carboxylate → 4-(1-Allyl-pyrrolidin-2-yl)-phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 2-(4-aminophenyl)pyrrolidine-1-carboxylate | HCID 44607625 | — |
| Reactant | 1-Allyl-2-(4-bromo-phenyl)-pyrrolidine | HCID 51358514 | — |
| Product | 4-(1-Allyl-pyrrolidin-2-yl)-phenylamine | HCID 59300236 | 87% |
Reaction Steps
Using the same procedure described for the preparation of 2-(4-Amino-phenyl)-pyrrolidine-1-carboxylic acid tert-butyl ester, the title compound is prepared from 1-Allyl-2-(4-bromo-phenyl)-pyrrolidine (470 mg, 1.77 mmol) in 87% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07713994B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-eb038161912042d88aa2d57b7d60aaf5 |
| Source note | uspto-grants-2010_05 |