反应详情

Using the procedure described for the preparation of 4-{[4(4-methyl-piperazin-1-yl)-phenylamino]-methylene}-1,3-dioxo-1,2,3,4-tetrahyro-isoquinolin-6-yl)-carbamic acid 4-nitro-phenyl ester 5 g (26.0 mmol) of para-nitroanilin and 4-nitrophenyl chloroformate 14.6 g (72.4 mmol) were reacted to give (4-nitro-phenyl)-carbamic acid 4-nitro-phenyl ester, 11.0 g (100% yield) of yellow solid.

1. customwere reacted