HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Piperidin-1-ylmethyl)aniline → HCID 178518386, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Piperidin-1-ylmethyl)aniline | HCID 846150 | — |
| Reactant | (4E)-4-(Methoxymethylene)-6-nitroisoquinoline-1,3(2H,4H)-dione | HCID 59300161 | — |
| Reactant | HCID 178480603 | HCID 178480603 | — |
| Product | HCID 178518386 | HCID 178518386 | 73.3% |
Reaction Steps
Using the procedure described for (4Z)-4-[({3-chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]phenyl}amino)methylene]isoquinoline-1,3(2H,4H)-dione, 115 mg (0.46 mmol) of (4E)-4-(methoxy)methylene-6-nitroisoquinoline-1,3(2H,4H)-dione is reacted with 93 mg (0.49 mmol) of 4-piperidin-1-ylmethyl-phenylamine to give 137 mg (73%) of brown solid, mp 225-235 (dec); MS (ES−) m/z 405.2 (M−H)−1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07713994B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-a3bf621f18af45869bc63aa53bee845b |
| Source note | uspto-grants-2010_05 |