HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 178518266, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-(Aminomethyl)phenol--hydrogen chloride (1/1) | HCID 22058465 | — |
| Reactant | 4-methoxymethylene-6-bromo-4H-isoquinoline-1,3-dione | HCID 68692764 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178518266 | HCID 178518266 | 30% |
Reaction Steps
To a mixture of 6-bromo-4-methoxymethylene-4H-isoquinoline-1,3-dione (194 mg, 0.69 mmol) and 2-aminomethyl-phenol hydrochloride salt (110 mg, 0.69 mmol) in N,N-dimethylformamide (DMF) (5 mL) is added Et3N (0.145 mL, 1.04 mmol). The precipitate is filtered to give 76 mg (30%) of the title compound as a beige solid. MS (ESI) m/z 371.0 (M−H)−1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07713994B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-1dd1f45909744f29a7bd09100a06882a |
| Source note | uspto-grants-2010_05 |