HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminomethyl-4'-fluoro-biphenyl-2-ol → HCID 178518362, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminomethyl-4'-fluoro-biphenyl-2-ol | HCID 59299922 | — |
| Reactant | 4-methoxymethylene-6-iodo-4H-isoquinoline-1,3-dione | HCID 68691019 | — |
| Product | HCID 178518362 | HCID 178518362 | 60% |
Reaction Steps
Following the same procedure for the preparation of 4-{[(2-Hydroxy-biphenyl-4-ylmethyl)-amino]-methylene}-6-iodo-4H-isoquinoline-1,3-dione-2, the title compound is prepared from 6-iodo-4-methoxymethylene-4H-isoquinoline-1,3-dione (90 mg, 0.27 mmol) and 4-Aminomethyl-4′-fluoro-biphenyl-2-ol (66 mg, 0.3 mmol) in 60% yield: MS (ESI): 513.1 (M−1)−1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07713994B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-9a97f3278ed3462c9f33c07efe21df43 |
| Source note | uspto-grants-2010_05 |