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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2236874Generated: October 31, 2026

6-Iodoisoquinoline-1,3(2h,4h)-dione → HCID 178518366, compound

https://huagongshe.com/reaction/2236874

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Iodoisoquinoline-1,3(2h,4h)-dioneHCID 11266171—
Reactant5-Aminomethyl-2-furan-3-yl-phenolHCID 42625670—
Reactant4-methoxymethylene-6-iodo-4H-isoquinoline-1,3-dioneHCID 68691019—
ProductHCID 178518366HCID 17851836656%

Reaction Steps

Following the same procedure for the preparation of 4-{[(2-Hydroxy-biphenyl-4. -ylmethyl)-amino]-methylene}-6-iodo-4H-isoquinoline-1,3-dione, the title compound is prepared from 6-iodo-4-methoxymethylene-4H-isoquinoline-1,3-dione (85 mg, 0.26 mmol) and 5-Aminomethyl-2-furan-3-yl-phenol in 56% yield: MS (ESI): 487.1 (M+1)+1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07713994B2
Source datasetuspto-grants-2010_05
ORD IDord-07526fc657f7496fb6ef6a719152db94
Source noteuspto-grants-2010_05