HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59299973, compound → HCID 178483196, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59299973 | HCID 59299973 | — |
| Reactant | 4-methoxymethylene-6-iodo-4H-isoquinoline-1,3-dione | HCID 68691019 | — |
| Reactant | HCID 178518360 | HCID 178518360 | — |
| Product | HCID 178483196 | HCID 178483196 | 24% |
Reaction Steps
Following the same procedure for the preparation of 4-{[(2-Hydroxy-biphenyl-4-ylmethyl)-amino]-methylene}-6-iodo-4H-isoquinoline-1,3-dione, the title compound (purified through chromatography) is prepared from 6-iodo-4-methoxymethylene-4H-isoquinoline-1,3-dione (50 mg, 0.15 mmol) and 4-aminomethyl-3′-dimethylaminomethyl-biphenyl-2-ol (50 mg, 0.18 mmol) in 24% yield: MS (ESI): 554.0 (M+1)+1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07713994B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-0ce6be3025624900b36ce21df7555b67 |
| Source note | uspto-grants-2010_05 |