HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Aminomethyl-4-fluoro-2-furan-3-yl-phenol → HCID 178440614, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Aminomethyl-4-fluoro-2-furan-3-yl-phenol | HCID 59300092 | — |
| Reactant | 6-tert-Butyl-4-methoxymethylene-4H-isoquinoline-1,3-dione | HCID 68692567 | — |
| Reactant | HCID 178518360 | HCID 178518360 | — |
| Product | HCID 178440614 | HCID 178440614 | 60% |
Reaction Steps
Following the same procedure for the preparation of 4-{[(2-Hydroxy-biphenyl-4-ylmethyl)-amino]-methylene}-6-iodo-4H-isoquinoline-1,3-dione, the title compound is prepared from 6-tert-Butyl-4-methoxymethylene-4H-isoquinoline-1,3-dione (11 mg, 0.042 mmol) and 5-Aminomethyl-4-fluoro-2-furan-3-yl-phenol (12 mg, 0.058 mmol) in 60% yield: MS (ESI): 433.2 (M−1)−1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07713994B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-320bce8c841c494d8755f02f31dd3dc1 |
| Source note | uspto-grants-2010_05 |