Acetic Acid → HCID 70543246, compound

HRID 223693Notes

Reaction equation

HRID 223693 reaction equation
C(OC([NH:8][C@H:9]([C:13]([NH:15][C@H:16]([C:20]([NH:22][C@H:23]([C:34]([OH:36])=[O:35])[CH2:24][C:25]1[C:33]2[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=2)[NH:27][CH:26]=1)=[O:21])[CH:17]([CH3:19])[CH3:18])=[O:14])[CH:10]([CH3:12])[CH3:11])=O)(C)(C)C.C(O)(=O)C.[ClH:41].O>O1CCOCC1>[ClH:41].[NH2:8][C@H:9]([C:13]([NH:15][C@H:16]([C:20]([NH:22][C@H:23]([C:34]([OH:36])=[O:35])[CH2:24][C:25]1[C:33]2[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=2)[NH:27][CH:26]=1)=[O:21])[CH:17]([CH3:19])[CH3:18])=[O:14])[CH:10]([CH3:11])[CH3:12]

Participants

6

Reactant 4

HCID 176Acetic AcidHCID 313Hydrochloric AcidHCID 962WaterHCID 54549985HCID 54549985, compound

Product 1

HCID 70543246HCID 70543246, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

The title compound was prepared using the previously described process using the following reagants: 0.85 grams (1.7 mmoles) t-butyloxycarbonyl-Valyl-valyl-tryptophan, 6 ml glacial acetic acid and 3 ml 5.68 N HCl in dioxane Total yield was 0.75 grams (100 percent). Anaylsis calculated for C21H30N4O4.HCl.1/3 H2O: C, 56.69; H, 7.17; N, 12.59. Found: C, 57.06; H, 7.3; N, 12.17.

Sources & evidence

ORD record
ord-8882fb2794f34fd8ba688ec9f0542b3a
Source dataset
uspto-grants-1982_10
Patent number
US04356118

Reaction notes

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